The injury occurred during Manchester City’s 3-2 victory over Ipswich Town in the English Premier League, where Semenyo was introduced as a 77th-minute substitute for Jeremy Doku.

Despite completing the match, the forward showed visible discomfort and went straight down the tunnel at the final whistle before undergoing detailed medical scans. Subsequent evaluations confirmed a left knee collateral ligament injury, though initial fears of a more severe tear were allayed.

Speaking ahead of his side’s UEFA Champions League match against AEK Athens,Manchester City manager Enzo Maresca provided clarity on the diagnosis and expected timeline.

The only one that will be out for probably eight weeks is Antoine [Semenyo]," Maresca confirmed.

"In the first moment we expected a worse injury. After yesterday's scan we feel much better because it's not so big like we expected. It will be eight weeks. Now the most important thing is recovery. When he is back in December it will be like a new player.

Semenyo’s absence leaves a noticeable void in attack for both club and country. Since joining Manchester City from Bournemouth, the Ghanaian international has made a sharp impact, registering two goals and three assists in nine appearances across all competitions, including five goal contributions in six starts.

His temporary absence forces Manchester City to navigate a congested fixture list—including Champions League ties against AEK Athens, RB Leipzig, Napoli, and Barcelona, alongside key Premier League tests against Aston Villa, Brighton, Nottingham Forest, Fulham, and Arsenal—without one of their most dynamic wide options.

For the Black Stars of Ghana,the timing of Semenyo’s injury could hardly be more challenging. Having already missed Ghana’s September–October qualifying fixtures due to an ankle problem, the forward is now officially sidelined for the upcoming AFCON 2027 qualifying doubleheader against Somalia scheduled between November 10 and November 18.

With Ghana currently sitting at the bottom of Group C in their qualifying group, securing positive results in the two fixtures against Somalia on November 11 and November 15 is vital to keeping their tournament qualification hopes alive.

Technical handlers for the Black Stars must now recalibrate their tactical approach and seek alternative attacking solutions in Semenyo's absence as the player focuses on his rehabilitation targeting a return in December.

Antoine Semenyo’s two-month layoff presents a stern test for both Manchester City’s squad depth and Ghana’s AFCON qualification campaign. While the diagnosis of a collateral ligament injury is a setback, manager Enzo Maresca's optimism regarding a full return in December provides a silver lining for fans eager to see the energetic forward back on the pitch. For Ghanaian supporters, all eyes now turn to the Black Stars’ technical team to see how they adapt ahead of the must-win doubleheader against Somalia.